Author

Thomas Holm Pedersen

Aarhus UniversityORCID 0000-0002-1060-4989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Anders RiisageriD· 1 shared Jacob Nørgaard Poulsen· 1 shared Jakob WangiD· 1 shared Jeppe Seamus BayleyiD· 1 shared Jesper Emil JakobsgaardiD· 1 shared Johan PalmfeldtiD· 1 shared Johannes OvergaardiD· 1 shared Jon HerskindiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Anders RiisagerORCID

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2 papers

Recent·Most cited

The muscle atrophic phenotype of MuSK myasthenia gravis: Insights from a preclinical rat model

Jesper Emil Jakobsgaard, Pernille Bogetofte Thomasen, Jakob Wang, Thea H. Kristiansen, Pernille Johnsen, Anders Riisager, Nete Huus, Martin Broch‐Lips, Martin Brandhøj Skov, Johan Palmfeldt, Thomas Holm Pedersen, Kristian Vissing

This study uses a rat model to show that MuSK autoimmunity causes fiber-type-selective muscle atrophy and proteome remodeling, with mitochondrial and translational dysregulation as key features.

bioRxiv · Mar 16, 2026 · PreprintMolecular Biology

Chill tolerant Drosophila species maintain electrogenic muscle membrane potential to resist cold-induced depolarization

Johannes Overgaard, Jeppe Seamus Bayley, Jacob Nørgaard Poulsen, Nikolaj Johannes Skole Jensen, Thomas Holm Pedersen, Jon Herskind, Mads Kuhlmann Andersen

This study examines how Na+/K+-ATPase activity maintains muscle membrane potential in Drosophila species under different temperatures, finding that cold-tolerant species retain this electrogenic effect while sensitive species lose it.

Journal of Experimental Biology · Oct 2, 2025Peer-reviewedPhysiology