Cancer BiologybioRxivPreprint
Leukaemia cell intrinsic and extrinsic factors cooperate to facilitate the survival and proliferation of KMT2A-rearranged B-ALL in the CNS niche.
Alasdair Duguid, Camille Malouf, Leslie Nitsche…·Katrin Ottersbach
This study identifies miR-93 as a key regulator of KMT2A-rearranged B-ALL survival in the CNS niche through transcriptomic and immune profiling in a murine model.
DOI 10.1101/2024.12.03.626602