Author

Chrysa Kapeni

University of CambridgeORCID 0000-0003-0408-2106Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alastair Morris KilpatrickiD· 1 shared Anne Christin MacheliD· 1 shared Bahar Mirshekar-SyahkaliD· 1 shared Berthold GöttgensiD· 1 shared Camille MaloufiD· 1 shared Dilyara Sabirova· 1 shared Flavio BekeiD· 1 shared Kankan Xia· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Alastair Morris KilpatrickORCID

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2 papers

Recent·Most cited

ImmunologyScience ImmunologyPeer-reviewedJul 11, 2025

Hedgehog signaling controls cytotoxic T cell migration in the tumour microenvironment.

Chrysa Kapeni, Louise M. O’Brien, Dilyara Sabirova…·Maike de la Roche

This study shows that Hedgehog signaling via Smo regulates CD8 T cell migration into tumors, explaining why Hh inhibitors fail in solid cancers.

2 citations

mouseexperimental assay

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Developmental BiologybioRxivPreprintSep 13, 2021

p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

Chrysa Kapeni, Leslie Nitsche, Alastair Morris Kilpatrick…·Katrin Ottersbach

The paper shows p57Kip2 limits HSC numbers by restricting SNS progenitor size and catecholamine secretion in the AGM region via β2-adrenergic signaling.

DOI 10.1101/2021.09.13.459835

mousebulk RNA-seq

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