Anti-inflammatory treatment with FTY720 starting after onset of symptoms reverses synaptic and memory deficits in an AD mouse model
Georgia-Ioanna Kartalou, Ana Rita Salgueiro Pereira, Thomas Endres, Angelina Lesnikova, Plinio Cabrera Casarotto, Paula A. Pousinha, Kévin Delanoe, Elke Edelmann, Eero Ċastrén, Kurt Gottmann, Hélène Marie, Volkmar Leßmann
This study shows that FTY720 treatment after symptom onset in an AD mouse model improves synaptic and memory deficits through anti-inflammatory effects.
International Journal of Molecular Sciences · Nov 25, 2020Peer-reviewedNeuroscience