Developmental BiologyNature CommunicationsPeer-reviewed
Single cell RNA-seq and ATAC-seq indicate critical roles of Isl1 and Nkx2-5 for cardiac progenitor cell transition states and lineage settlement
Guangshuai Jia, Jens Preussner, Xi Xian Chen…·Thomas W Braun
The paper uses single-cell RNA-seq and ATAC-seq to study cardiac progenitor cell fate transitions, identifying roles for Isl1 and Nkx2-5 in lineage commitment and gene regulatory networks.