Author

Michail Yekelchyk

Max Planck Institute for Heart and Lung ResearchORCID 0000-0003-4792-4131Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Stefan GüntheriD· 2 shared Thomas W BrauniD· 2 shared Andreas Michael ZeiheriD· 1 shared Ariane FischeriD· 1 shared Carsten Tobias KuenneiD· 1 shared Christian KupattiD· 1 shared David JohniD· 1 shared David Rodríguez MoralesiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Stefan GüntherORCID

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2 papers

Recent·Most cited

Endothelial expression of ZBTB16 protects against cardiac aging

Kathrin A. Stilz, Vincent Elvin Leonard, David Rodríguez Morales, Simone-Franziska Glaser, Veronica Larcher, Mariano Ruz Jurado, Pedro Felipe Malacarne, Nivethitha Manickam, Lukas Stefan Tombor, Wesley Tyler Abplanalp, Josefine Panthel, Haris Kujundzic, Ariane Fischer, Katja Schmitz, Oliver J Mueller, , Stefanie Dimmeler

This study identifies ZBTB16 as a critical regulator of endothelial function in aging, showing its protective role against cardiac dysfunction through suppression of pro-fibrotic signaling.

bioRxiv · Oct 8, 2025 · PreprintCell Biology

Single cell RNA-seq and ATAC-seq indicate critical roles of Isl1 and Nkx2-5 for cardiac progenitor cell transition states and lineage settlement

Guangshuai Jia, Jens Preussner, Xi Xian Chen, Stefan Günther, Xuejun Yuan, Michail Yekelchyk, Carsten Tobias Kuenne, Mario Looso, Yonggang Zhou, Sarah Amalia Teichmann, Thomas W Braun

The paper uses single-cell RNA-seq and ATAC-seq to study cardiac progenitor cell fate transitions, identifying roles for Isl1 and Nkx2-5 in lineage commitment and gene regulatory networks.

Nature Communications · Nov 13, 2018Peer-reviewedDevelopmental Biology