Jens Preussner

The paper identifies HIF1α-AS1 as a DNA:DNA:RNA triplex-forming lncRNA that interacts with the HUSH complex to repress gene expression and modulates angiogenesis in pulmonary hypertension.

i2dash creates customizable, interactive web dashboards for visualizing omics data, integrating with R-based analysis pipelines and supporting single-cell RNA-seq workflows.

multicrispr is a gRNA design tool that enables efficient and specific gRNA creation for CRISPR-based applications like Prime Editing and large-scale screening.

TOBIAS enables genome-wide analysis of TF binding dynamics using ATAC-seq data, revealing complex TF interactions during zygotic genome activation in humans and mice.

The paper uses single-cell RNA-seq and ATAC-seq to study cardiac progenitor cell fate transitions, identifying roles for Isl1 and Nkx2-5 in lineage commitment and gene regulatory networks.

This study identifies Myh10 as critical for alveolar development and ECM remodeling, linking its deficiency to pulmonary disease and emphysema.

This study identifies KCNJ13 as critical for tracheal tubulogenesis by maintaining ion homeostasis and actin polymerization in smooth muscle cells.

The paper introduces a web-based GUI for the UROPA tool to simplify genomic region annotation for biologists and clinicians.