Molecular BiologybioRxivPreprint
Potent Cas9 inhibition in bacterial and human cells by new anti-CRISPR protein families
Jooyoung Lee, Aamir Mir, Alireza Edraki…·Erik J. Sontheimer
The paper identifies and characterizes two new anti-CRISPR protein families that inhibit type II-C Cas9 systems, showing potent inhibition of NmeCas9 and cross-species activity.