MUC2 Expression Modulates Immune Infiltration in Colorectal Cancer
Christophe Michel Raynaud, Ayesha Jabeen, Eiman I. Ahmed, Satanay Hubrack, Apryl Sanchez, Shimaa Sherif, Ahmad Al‐Shaibi, Jessica P Roelands, Bernice Lo, Davide Bedognetti, W. R. L. Hendrickx
This study investigates how MUC2 expression affects immune infiltration in colorectal cancer using in vitro models and CRISPR knockout, finding that MUC2 loss increases immune infiltration only in HT-29 cells.
Frontiers in Immunology · Jan 24, 2025Peer-reviewedCancer Biology