Author

Xuchen Zhang

Howard Hughes Medical InstituteORCID 0000-0002-1088-4757Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Thomas Christian SüdhofiD· 1 shared Xudong CheniD· 1 shared Yi MiaoiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperNeuroscience

Thomas Christian SüdhofORCID

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1 paper

Recent·Most cited

NeurosciencebioRxivPreprintJul 15, 2026

Teneurins Are SPARCL1 Receptors

Xuchen Zhang, Xudong Chen, Yi Miao, Thomas Christian Südhof

This study identifies teneurins as SPARCL1 receptors and shows that SPARCL1 enhances synapse formation by binding to teneurins via its follistatin-like domain and activating synapse formation via its Ca2+-binding domain.

DOI 10.64898/2026.07.13.738299

mouseexperimental assay

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