Author

Xudong Chen

Howard Hughes Medical InstituteORCID 0000-0002-9433-3732Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xudong Chen1 paper · Central South University

Biology Disciplines

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Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alan Sheng-Hwa TungiD· 1 shared Arthur GermakovskiiD· 1 shared Chao Lin· 1 shared Hannah T. CessnaiD· 1 shared Jacob Tondreau· 1 shared Jan SpaasiD· 1 shared Jason A. SprowliD· 1 shared Jonathan Z. LongiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Alan Sheng-Hwa TungORCID

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2 papers

Recent·Most cited

MCT6 is an intestinal Lac-Phe exporter required for metformin-associated weight loss

Shuke Xiao, Alan Sheng-Hwa Tung, Jan Spaas, Sipei Fu, Xudong Chen, Tuan Kiet Trinh, María Dolores Moya-Garzón, Veronica L. Li, Hannah T. Cessna, Kentaro Ito, Saranya C. Reghupathy, Chao Lin, Xuchao Lyu, Steffen Henning Raun, Miles D.W. Tyner, , Jonathan Z. Long

This study identifies MCT6 as an intestinal exporter of Lac-Phe, showing its role in metformin-induced weight loss and systemic metabolite regulation.

bioRxiv · Sep 28, 2026 · PreprintPhysiology

Teneurins Are SPARCL1 Receptors

Xuchen Zhang, Xudong Chen, Yi Miao, Thomas Christian Südhof

This study identifies teneurins as SPARCL1 receptors and shows that SPARCL1 enhances synapse formation by binding to teneurins via its follistatin-like domain and activating synapse formation via its Ca2+-binding domain.

bioRxiv · Jul 15, 2026 · PreprintNeuroscience