Author

Rafael Tabarés‐Seisdedos

Universitat de ValènciaORCID 0000-0002-1089-2204Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Alfonso ValenciaiD· 4 shared Jon Sánchez-ValleiD· 4 shared Héctor TejeroiD· 2 shared Jaume Forés-MartosiD· 2 shared María Flores-RoderoiD· 2 shared Véra PancaldiiD· 2 shared Anaı̈s BaudotiD· 1 shared Celso ArangoiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersBioinformatics

Alfonso ValenciaORCID

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Author profile →

4 papers

Recent·Most cited

A Genetic Atlas of Direct and Inverse Neuropsychiatric-Cancer Comorbidity

María Flores-Rodero, Jaume Forés-Martos, Joan Vicent Sánchez‐Ortí, Salvador Martı́nez, Frank Winkler, Alfonso Valencia, Rafael Tabarés‐Seisdedos, Jon Sánchez-Valle

The paper identifies genetic correlations between neuropsychiatric disorders and cancers, revealing shared and opposing biological mechanisms.

bioRxiv · Jul 11, 2026 · PreprintGenomics

Sex-specific transcriptome similarity networks elucidate comorbidity relationships

Jon Sánchez-Valle, María Flores-Rodero, Felipe Xavier Costa, Jose Carbonell-Caballero, Iker Núñez-Carpintero, Rafael Tabarés-Seisdedos, Luis Mateus Rocha, Davide Cirillo, Alfonso Valencia

The paper identifies sex-specific transcriptomic similarities between comorbid diseases and finds that 13-16% of disease pairs show sex-specific transcriptome similarity, recapitulating 53-60% of known sex-specific comorbidities.

Communications Medicine · Dec 30, 2025Peer-reviewedBioinformatics

Transcriptomic metaanalyses of autistic brains reveals shared gene expression and biological pathway abnormalities with cancer.

Jaume Forés-Martos, Ferrán Catalá-López, Jon Sánchez-Valle, Kristina Ibáñez, Héctor Tejero, Helena Palma‐Gudiel, Joan Climent, Véra Pancaldi, Lourdes Fañanás, Celso Arango, Mara Parellada, Anaı̈s Baudot, Daniel L. Vogt, John L.R. Rubenstein, Alfonso Valencia, Rafael Tabarés‐Seisdedos

The paper compares gene expression profiles of ASD and 22 cancer types, finding shared and opposing deregulations in specific cancers and common biological pathways.

Molecular Autism · Apr 8, 2019Peer-reviewedSystems Biology

Unveiling the molecular basis of disease co-occurrence: towards personalized comorbidity profiles

Jon Sánchez-Valle, Héctor Tejero, José M. Fernández, David Juan, Salvador Capella-Gutiérrez, Fátima Al‐Shahrour, Rafael Tabarés‐Seisdedos, Véra Pancaldi, Alfonso Valencia

The paper constructs a disease interaction network from patient molecular profiles to uncover molecular mechanisms of comorbidity and identify associated genes and drugs.

bioRxiv · Oct 3, 2018 · PreprintBioinformatics