Celso Arango

The paper examines the relationship between white matter microstructure, measured by fractional anisotropy, and transition to psychosis in individuals at clinical high risk, finding directionally consistent but small associations.

Ultra-rare damaging coding variants in 87,959 schizophrenia cases and 150,587 controls implicate 40 genes (16 exome-wide, 24 at 5% FDR), half overlapping autism, developmental delay or bipolar genes.

This study identifies shared genetic architecture between schizophrenia and substance use disorders using GWAS and genomic methods, finding significant genetic correlations and bidirectional causal relationships.

The paper examines longitudinal white matter changes in early psychosis using diffusion tensor imaging and finds no significant group differences or associations with symptom progression, but links antipsychotic medication dose to lower fractional anisotropy.

The paper introduces co-expression-based models to improve eQTL predictions and identifies novel schizophrenia-associated genes using brain RNA-seq data.

This study investigates brain age differences in youth with conduct disorder compared to controls, finding accelerated brain maturation in those with adolescence-onset CD.

This study links sulcal widening in schizophrenia to network hubs and genes involved in synaptic signaling and energy metabolism.

This study identifies 77 genetic loci associated with suicidality through genome-wide association analyses across multiple cohorts and provides biological insights into its genetic architecture.

The paper examines morphometric similarity networks in health and schizophrenia, finding reduced default mode network similarity in schizophrenia but minimal individual deviations over time.

This study replicates and extends findings linking social dysfunction to reduced default mode network connectivity in schizophrenia, Alzheimer's disease, and major depressive disorder.

This study identifies novel genetic risk loci for COVID-19 hospitalization in admixed American populations through a large GWAS.

The paper demonstrates a data harmonization process for memory testing across 53 studies, reducing inter-site variance while preserving covariate effects.

This study uses fMRI and TMS to investigate the roles of prefrontal and parietal cortex in task-switching, finding distinct functions for the aIFJ and IPS in preparatory control.

The paper examines longitudinal allometric scaling of sulcal morphology in health and schizophrenia, finding steeper age-related declines in SZ compared to healthy individuals.

The paper examines hemispheric asymmetry in structural covariance networks in ASD across 43 datasets, finding altered topological features in specific brain regions.

The paper investigates the conservation of rare schizophrenia risk variants across diverse populations and finds consistent burden in constrained genes.

The paper examines sex differences in lifespan trajectories and variability of human sulcal and gyral morphology using longitudinal neuroimaging data.

The paper identifies a subgroup of schizophrenia patients with extreme cognitive deficits by analyzing sulcal width dissimilarity using the PBSI-SW metric.

This study examines whether cannabis use extent predicts psychotic-like and euphoric intoxication experiences in First Episode Psychosis patients and controls, finding a significant interaction between caseness and use frequency.

The paper investigates associations between polygenic risk scores for schizophrenia, psychotic-like experiences, and structural brain network properties in healthy UK Biobank participants.

The paper investigates the relationship between jumping to conclusions bias, IQ, psychosis, and polygenic risk scores in a case-control study, finding that IQ significantly predicts JTC bias while schizophrenia PRS does not.

The paper examines structural brain differences in children and adolescents with aggressive behavior, finding subtype-specific volume reductions in regions linked to decision making and empathy.

The paper examines the independent and combined effects of schizophrenia polygenic risk score and heavy cannabis use on psychotic disorder risk using EUGEI data, finding both factors independently increase risk.

This study identifies altered structural brain asymmetry in autism spectrum disorder using a large-scale meta-analysis of MRI data from 1,774 ASD cases and 1,809 controls.

This study identifies genetic variants associated with sociability as a continuous trait and finds genetic correlations with schizophrenia, major depressive disorder, and autism spectrum disorders.

This study compares structural brain differences across ADHD, ASD, and OCD using MRI data from multiple cohorts, finding disorder-specific alterations in brain volume and cortical thickness.

The paper analyzes rare and common alleles in schizophrenia trios, identifying rare missense variants in SLC6A1 and confirming the role of neurodevelopmental disorder genes.

The paper compares gene expression profiles of ASD and 22 cancer types, finding shared and opposing deregulations in specific cancers and common biological pathways.

The paper examines functional connectivity differences in children and adolescents with disruptive behavior, finding distinct patterns for reactive and proactive aggression and callous-unemotional traits, emphasizing the role of comorbid symptoms.