Frank Winkler

The paper identifies genetic correlations between neuropsychiatric disorders and cancers, revealing shared and opposing biological mechanisms.

The paper shows brain metastases form gap-junction-coupled networks with coordinated calcium activity that drives proliferation and is inhibited by gap junction blockers.

The paper introduces molecular recorders to track kinase activity in cells and applies them to study PKA activity and neuromodulation.

This study uses single-cell multiomics to identify regulatory programs and plasticity regulators in glioblastoma, revealing MYT1L as a key repressor of malignant plasticity.

The paper shows neurons form direct excitatory synapses with brain-metastatic breast and melanoma cancer cells, supporting metastasis and offering new therapeutic targets.

This study shows glioblastoma cells deplete Wnt signaling from neurons, leading to tumor growth and neurodegeneration in Drosophila and human xenograft models.