Author

Davide Lacarbonara

Columbia UniversityORCID 0000-0002-1090-6899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

Dawid S. ZylaiD· 3 shared Erica Ollmann SaphireiD· 3 shared Gele NiemeyeriD· 3 shared Kathryn M. HastieiD· 3 shared Marissa Danielle AccianiiD· 3 shared Matteo PorottoiD· 3 shared Stefan NiewieskiD· 3 shared Alexander L. GreningeriD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Dawid S. ZylaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural and Mechanistic Basis for Antibody Neutralization of the Measles Fusion Protein

Dawid S. Zyla, Roberta Della Marca, Davide Lacarbonara, Gele Niemeyer, Gillian Zipursky, Laura Di Clemente, Mare H. L. Verbruggen, Laura L.A. van Dijk, Oscar Martinez Ceh, Gabriella Jonathan-Trakht, Gavreel Kalantarov, Marissa Danielle Acciani, Giulia Laterza, Dariia Vyshenska, Cameron Leedale, , Matteo Porotto

This study identifies neutralizing epitopes on the measles virus fusion protein by analyzing monoclonal antibodies and their structural interactions with prefusion and postfusion conformations.

Nature Communications · Apr 6, 2026Peer-reviewedImmunology

Stabilized Full-Length Measles Fusion Protein Elicits Potent Immunity and Protection In Vivo

Dawid S. Zyla, Gillian Zipursky, Roberta Della Marca, Davide Lacarbonara, Gele Niemeyer, Weiwei Peng, Camilla Predella, Kyle N. Stearns, Cameron Leedale, Jonathan L Miller, Daniel Tay, Jonathan Kao, Marissa Danielle Acciani, Laura Di Clemente, Anirban Das, , Matteo Porotto

This study designs and tests a stabilized full-length measles fusion protein antigen that induces strong neutralizing antibodies and protects against viral challenge in a cotton rat model.

bioRxiv · Oct 7, 2025 · PreprintImmunology

Uncovering the features of Measles-targeting human antibodies elicited by the MMR vaccine

Marissa Danielle Acciani, Dawid S. Zyla, Gele Niemeyer, Stephanie Harkins, Diptiben V. Parekh, Emily Pawlack, Davide Lacarbonara, Stefan Niewiesk, Matteo Porotto, Kathryn M. Hastie, Erica Ollmann Saphire

This study identifies and characterizes human monoclonal antibodies against measles virus surface proteins, revealing their epitopes and mechanisms of neutralization.

bioRxiv · Sep 9, 2025 · PreprintImmunology