Stefan Niewiesk

This study identifies neutralizing epitopes on the measles virus fusion protein by analyzing monoclonal antibodies and their structural interactions with prefusion and postfusion conformations.

This study designs and tests a stabilized full-length measles fusion protein antigen that induces strong neutralizing antibodies and protects against viral challenge in a cotton rat model.

This study identifies and characterizes human monoclonal antibodies against measles virus surface proteins, revealing their epitopes and mechanisms of neutralization.

The paper presents a chromosome-level genome assembly of the Hispid cotton rat, annotating 24,878 protein-coding genes and identifying genetic innovations.

This study shows that a mature human immune system in humanized mice, developed over 3-4 months, leads to worse spinal cord injury outcomes due to increased neuroinflammation.