Sheng Ye

Porcine extended pluripotent stem cell-derived somite-like mesoderm cells with Dox-driven PAX7 are robust seed cell resource for facilitating production of cultured meat

This paper establishes a method to generate porcine somite-like mesodermal cells with Dox-driven PAX7 for efficient muscle differentiation, enabling scalable cultured meat production.

Modeling structural variations sequencing information to address missing heritability and enhance risk prediction

The paper develops SVrefiner to refine structural variations, enhancing heritability estimates and risk prediction by integrating refined SVs with SNPs and other variants.

Homodimerized Arpins: Binding to Arp2/3 Complexes with Positive Synergy to Inhibit Lamellipodia-Dependent Tumor Metastasis

This study reveals that Arpin homodimerization enhances inhibition of Arp2/3 complex-mediated actin polymerization, suppressing cancer cell migration and metastasis.