Author

Inmaculada Spiteri

Institute of Cancer ResearchORCID 0000-0002-1097-8972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A.-M. Baker· 1 shared Andrea SottorivaiD· 1 shared Ann‐Marie BakeriD· 1 shared Christopher KimberleyiD· 1 shared Claire LynniD· 1 shared Eszter LakatosiD· 1 shared Jacob HousehamiD· 1 shared JOHN BRIDGEWATER· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A.-M. Baker

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1 paper

Recent·Most cited

Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer

Eszter Lakatos, Vinaya Gunasri, Luis Zapata, Jacob Househam, Timon Heide, Nicholas Trahearn, Ottilie Swinyard, Luis Humberto Cisneros, Claire Lynn, Maximilian Mossner, Christopher Kimberley, Inmaculada Spiteri, Maurice P.H.M. Jansen, Manuel Rodriguez‐Justo, Miriam Mitchison, , Trevor A. Graham

This study shows that immune evasion in colorectal cancer follows a 'Big Bang' pattern, where early genetic and epigenetic changes drive subsequent tumor-immune evolution.

Nature Genetics · Jun 1, 2024Peer-reviewedCancer Biology