Author

Sheetal S. Sawant

Duke UniversityORCID 0000-0002-1109-7907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Georgia D. TomarasiD· 2 shared Agnes M. Harskamp· 1 shared Aimee A. DesrosiersiD· 1 shared Albert CupoiD· 1 shared Alex C. Sullivan· 1 shared Alicia SatoiD· 1 shared Alison BenneriD· 1 shared Andrew B. WardiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Georgia D. TomarasORCID

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2 papers

Recent·Most cited

Sequential vaccination matures VRC01-class HIV-1 neutralizing antibodies in humans

Tom G. Caniels, Madhu S. Prabhakaran, Sashank Agrawal, Kellie J. MacPhee, Rhianna Bronson, Weiwei Wu, Eva I.M. Schumacher, Swastik Phulera, Katrina G. Millard, Deanna Dong, Martina Turroja, Aimee A. Desrosiers, Jeffrey Michael Bethony, Elissa M. Malkin, Annelou van der Veen, , Rogier W. Sanders

This study shows that sequential vaccination can mature VRC01-class B cells into antibodies that neutralize a broad range of HIV-1 viruses.

bioRxiv · Oct 26, 2026 · PreprintImmunology

Monocyte-derived transcriptome signature indicates antibody-dependent cellular 1 phagocytosis as the primary mechanism of vaccine-induced protection against HIV-1

Shida Shangguan, Philip K. Ehrenberg, Aviva Geretz, Lauren K. Yum, Gautam Kundu, Kelly May, Slim Fourati, Krystelle Nganou‐Makamdop, LaTonya D. Williams, Sheetal S. Sawant, Éric Lewitus, Punnee Pitisuttithum, Sorachai Nitayaphan, Suwat Chariyalertsak, Supachai Rerks‐Ngarm, , Rasmi Thomas

The paper identifies a monocyte-derived transcriptome signature linked to antibody-dependent cellular phagocytosis as a correlate of vaccine-induced protection against HIV-1 in clinical trials.

eLife · Sep 17, 2021Peer-reviewedSystems Biology