Author

María‐Dolores Chiara

Universidad de OviedoORCID 0000-0002-1112-1583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Lucía CeladaiD· 2 shared Tamara CubiellaiD· 2 shared Alexander R. OpotowskyiD· 1 shared Alexandre BuffetiD· 1 shared Álvaro Suárez‐Priede· 1 shared Amelia OleagaiD· 1 shared Ana Belén Moreno-CárdenasiD· 1 shared Ana González GarcíaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Lucía CeladaORCID

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2 papers

Recent·Most cited

Cancer BiologyCell Death and DiseasePeer-reviewedMar 26, 2026

PCDHGC3 silencing promotes renal carcinoma metastasis via mTOR/HIF2a and lipid metabolism rewiring

Lucía Celada, Tamara Cubiella, Jaime San‐Juan‐Guardado…·María‐Dolores Chiara

This study shows that silencing PCDHGC3 promotes renal carcinoma metastasis through mTOR/HIF2a activation and lipid metabolism changes.

3 citationstop 4%

humanproteomics

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Cancer BiologyCancer DiscoveryPeer-reviewedApr 8, 2025

Convergent genetic adaptation in human tumors developed under systemic hypoxia and in populations living at high altitudes

Carlota Arenillas, Lucía Celada, José Ruiz-Cantador…·Rodrigo Almeida Toledo

This study links EPAS1HIF2 genetic adaptations in high-altitude populations to similar mutations in hypoxia-driven tumors, showing shared mechanisms in hypoxia response and tumorigenesis.

14 citations

humanbulk RNA-seq

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