Author

Helen Alexandra Shaw

Medicines and Healthcare products Regulatory AgencyORCID 0000-0002-1129-2075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

Helge C. DorfmuelleriD· 2 shared Mark ReglinskiiD· 2 shared Sarah ThomsoniD· 2 shared Sowmya Ajay CastroiD· 2 shared Alessandro RudaiD· 1 shared Azul ZorzoliiD· 1 shared Benjamin H. MeyeriD· 1 shared Brendan William WreniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Helge C. DorfmuellerORCID

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2 papers

Recent·Most cited

MicrobiologyVaccine XPeer-reviewedJun 11, 2025

Rhamnose Polysaccharide-Decorated Outer Membrane Vesicles as a Vaccine Candidate Targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Sowmya Ajay Castro, Sarah Thomson, Helen Alexandra Shaw…·Helge C. Dorfmueller

This study develops RhaPS-decorated OMVs as a universal Strep A vaccine candidate, showing immunogenicity and antibody recognition in animal models.

1 citation

𝕏 PostBluesky

Microbiologynpj VaccinesPeer-reviewedJan 22, 2025

A platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines

Sowmya Ajay Castro, Ian J. Passmore, Didier A. Ndeh…·Helge C. Dorfmueller

This study develops a platform for recombinant production of Group A Streptococcus glycoconjugate vaccines using E. coli, confirming their structural integrity and immunogenicity in animal models.

16 citationstop 5%

E. coliexperimental assay

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