Kandice Tanner

Viscous mechanical cues encode metastatic behavior through cytoskeletal-nuclear coupling and chromatin remodeling

This study shows that viscous mechanical cues influence cancer cell metastasis through cytoskeletal-nuclear coupling and chromatin remodeling.

Age dependent collective trafficking of tissue resident T cells in zebrafish

The paper uses intravital imaging in zebrafish to show age-dependent changes in collective T cell migration patterns in fins, linking tissue structure and immune function.

Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth

This study shows that synthetic spore-like particles (SSHELs) enhance T cell responses and reduce tumor growth in a mouse model by efficiently delivering peptides to dendritic cells.

Cell-specific cargo delivery using synthetic bacterial spores

This study demonstrates that SSHELs, synthetic bacterial spore-like particles, can deliver chemotherapy to HER2-positive cancer cells with reduced toxicity and effectiveness in tumor models.

Human macrophages survive and adopt activated genotypes in living zebrafish

This study shows human macrophages survive and adopt activated genotypes in zebrafish, mimicking cancer-related immune responses.