Author

David J. FitzGerald

National Institutes of HealthORCID 0000-0002-6589-0126Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Devorah L. Gallardo· 2 shared Domenico D’AtriiD· 2 shared Federico MachinandiarenaiD· 2 shared Kandice TanneriD· 2 shared Kumaran S. RamamurthiiD· 2 shared Minsuk KongiD· 2 shared Stephen M. HewittiD· 2 shared Alilin Mia· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersCancer Biology

Devorah L. Gallardo

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Immunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth

Domenico D’Atri, Elena Tondini, Federico Machinandiarena, Minsuk Kong, Alilin Mia, Devorah L. Gallardo, Kandice Tanner, Stephen M. Hewitt, David J. FitzGerald, Kumaran S. Ramamurthi

This study shows that synthetic spore-like particles (SSHELs) enhance T cell responses and reduce tumor growth in a mouse model by efficiently delivering peptides to dendritic cells.

mBio · Sep 12, 2025Peer-reviewedCancer Biology

Cell-specific cargo delivery using synthetic bacterial spores

Minsuk Kong, Domenico D’Atri, Maria Teresa Bilotta, Bailey Johnson, Taylor B. Updegrove, Devorah L. Gallardo, Federico Machinandiarena, I-Lin Wu, Maira A. Constantino, Stephen M. Hewitt, Kandice Tanner, David J. FitzGerald, Kumaran S. Ramamurthi

This study demonstrates that SSHELs, synthetic bacterial spore-like particles, can deliver chemotherapy to HER2-positive cancer cells with reduced toxicity and effectiveness in tumor models.

Cell Reports · Jan 1, 2023Peer-reviewedSynthetic Biology