Author

Florian J. Bock

Maastricht University Medical CentreORCID 0000-0002-1133-1767Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:imaging· 1 Assay:metabolomics· 1

Frequent Co-Authors

Jolanda A. F. Piepers· 1 shared Marc VooijsiD· 1 shared Rui ZhangiD· 1 shared Somaieh AhmadianiD· 1 shared Tom G. KeulersiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Jolanda A. F. Piepers

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1 paper

Recent·Most cited

Cell BiologyFEBS JournalPeer-reviewedMar 30, 2026

Disruption of Iron Metabolism Resulting from Dmt1/Slc11A2 Deficiency Compromises Notch Protein Degradation and Transcriptional Activation

Rui Zhang, Somaieh Ahmadian, Jolanda A. F. Piepers…·Marc Vooijs

This study shows that Dmt1 deficiency disrupts iron homeostasis, leading to lysosomal dysfunction and impaired Notch signaling by affecting NICD1 degradation and transcriptional activation.

1 citation

mouseproteomics

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