Computationally guided design of a metastasis-on-a-chip platform for quantitative evaluation of chemotactic cues in developmental cancers
Catherine Murphy, Luka Jarc, Alessia Cadavere…·Aránzazu Villasante
This paper develops a computationally guided metastasis-on-a-chip platform to evaluate chemotactic cues in cancer cells, finding that VEGF-C promotes migration in Ewing sarcoma and osteosarcoma while VEGF-A165 has no effect.