Author

Parker Knight

University of FloridaORCID 0000-0002-1141-3201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Assay:long-read sequencing· 1 Assay:scRNA-seq· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Rhonda L. BacheriD· 2 shared Alberto RivaiD· 1 shared Cara ArgusiD· 1 shared Carolina E Pardo· 1 shared Christina M. KendziorskiiD· 1 shared Eliza Morton· 1 shared Hadley Browder· 1 shared James Alexander ThomsoniD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Rhonda L. BacherORCID

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2 papers

Recent·Most cited

Enhancing biological signals and detection rates in single-cell RNA-seq experiments with cDNA library equalization

Rhonda L. Bacher, Li‐Fang Chu, Cara Argus, Jennifer M. Bolin, Parker Knight, James Alexander Thomson, Ron M. Stewart, Christina M. Kendziorski

This study shows that equalizing cDNA library concentrations before pooling improves gene detection rates and reduces technical artifacts in single-cell RNA-seq data.

Nucleic Acids Research · Oct 20, 2021Peer-reviewedGenomics

methylscaper: an R/Shiny app for joint visualization of DNA methylation and nucleosome occupancy in single-molecule and single-cell data

Parker Knight, Marie‐Pierre L. Gauthier, Carolina E Pardo, Russell P. Darst, Kevin Kapadia, Hadley Browder, Eliza Morton, Alberto Riva, Michael P. Kladde, Rhonda L. Bacher

The paper introduces methylscaper, an R/Shiny app for visualizing DNA methylation and nucleosome occupancy in single-molecule and single-cell data, showing its ability to identify biologically relevant chromatin features.

Bioinformatics · Jun 11, 2021Peer-reviewedBioinformatics