Author
University of FloridaORCID 0009-0002-1936-2231Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jason Orr Brant, Marie‐Pierre L. Gauthier, Christine E. Rodhouse…·Michael P. Kladde
The paper profiles chromatin accessibility in post-sepsis MDSCs, showing divergent epigenetic trajectories between rapid recovery and chronic critical illness, with MHC class II repression in CCI.
Christine Rodhouse, Evan L. Barrios, Leilani Zeumer-Spataro…·Clayton E. Mathews
This study identifies prolonged reduced oxidative metabolism and mitochondrial mass in CD66b+ leukocytes from sepsis patients, linked to adverse outcomes and gene silencing.
Han Sang Kim, Marie‐Pierre L. Gauthier, Aidan Higgs…·Robert Maile
This study identifies a biphasic epigenetic and transcriptional response in macrophages after burn injury, revealing locus-specific chromatin remodeling and immune dysfunction.
Angel M. Charles, Christine E. Rodhouse, Dijoia B. Darden…·Michael P. Kladde
This study maps epigenetic changes in MDSCs after sepsis, revealing age- and sex-specific chromatin remodeling linked to immune dysfunction.
Parker Knight, Marie‐Pierre L. Gauthier, Carolina E Pardo…·Rhonda L. Bacher
The paper introduces methylscaper, an R/Shiny app for visualizing DNA methylation and nucleosome occupancy in single-molecule and single-cell data, showing its ability to identify biologically relevant chromatin features.