Annalucia Serafino

This study shows reverse transcriptase inhibitors induce autophagy in cancer cells through LINE-1 ORF1p-dependent mechanisms involving DNA damage and lamin B1 interactions.

This study shows that 6-OHDA induces HERV-K activation in PD models, which is reduced by Wnt/β-catenin pathway modulation.

This study shows that FUS-induced splicing changes lead to cytoplasmic accumulation of hnRNP A2b/B1 splice variants, promoting stress granule formation and motor neuron toxicity in a mouse model of ALS.