Mark E. Schurdak

This study demonstrates that a vascularized liver acinus microphysiological system recapitulates key features of MASLD progression and lipid-induced hepatic insulin resistance.

This paper develops a coupled microphysiological system to study how liver dysfunction affects pancreatic islet function, finding altered secretomes and glucose responses under metabolic syndrome conditions.

This study uses a human liver microphysiology system to compare the effects of PNPLA3 variants on MASLD progression and drug response.