Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.
Asja Guzman, Tatsuya Kawase, Alexander J. Devanny…·Carol L. Prives
This study shows mutant p53 promotes cancer cell invasion in 3D environments via mevalonate pathway-dependent Rho/ROCK signaling and ECM reorganization.
5 citations