Author

Tatsuya Kawase

Astellas Pharma (Japan)ORCID 0000-0003-2253-2238Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexander J. Devanny· 1 shared Anil K. RustgiiD· 1 shared Asja GuzmaniD· 1 shared Carol L. PrivesiD· 1 shared Gizem EfeiD· 1 shared Iris G. MerceriD· 1 shared Karen YuiD· 1 shared Kausik RegunathiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexander J. Devanny

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1 paper

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedOct 21, 2025

Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling.

Asja Guzman, Tatsuya Kawase, Alexander J. Devanny…·Carol L. Prives

This study shows mutant p53 promotes cancer cell invasion in 3D environments via mevalonate pathway-dependent Rho/ROCK signaling and ECM reorganization.

5 citations

humanproteomics

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