BiophysicsbioRxivPreprint
From biting to engulfment: Target mechanics determines modes of phagocytosis through curvature--actin coupling
Shubhadeep Sadhukhan, Caitlin E. Cornell, Mansehaj Kaur Sandhu…·Nir S. Gov
This paper develops a theoretical model to simulate phagocytosis of deformable targets and identifies three mechanical regimes based on target stiffness, validated experimentally with GUVs and lymphoma cells.
DOI 10.64898/2026.01.28.702248