Daan Vorselen

This study shows that Myo1e/f regulate phagocytic podosomes and the phagocytic ring to ensure efficient cup closure in macrophages.

This paper develops a theoretical model to simulate phagocytosis of deformable targets and identifies three mechanical regimes based on target stiffness, validated experimentally with GUVs and lymphoma cells.

The paper introduces LipoTag, a chemical motif that enables functional imaging of plant cell membranes by making hydrophobic fluorophores water-soluble and wall-permeable.

This study shows that β2 integrins regulate macrophage phagocytosis based on cargo rigidity, acting as a mechanical checkpoint to control engulfment strategies.

The paper investigates how cells adapt to transport oversized parasitic cargo by reprogramming mechanical forces and subcellular architecture during migration.