Limited microglial metabolic improvement with time-restricted feeding in diet-induced obesity
Han Jiao, Jarne Jermei, Xian Liang…·Chun‐Xia Yi
This study examines how time-restricted feeding affects microglial immunometabolism in obese rats, finding that TRF during the active phase reduces fat mass and alters microglial transcriptome rhythmicity, but does not reverse HFD-induced metabolic inflexibility.