Chun‐Xia Yi

This study shows that Magel2 deficiency in a mouse model of Prader-Willi syndrome causes microglial structural changes and increased synaptic engulfment, altering neuron-microglia interactions and hypothalamic circuit function.

This study examines how time-restricted feeding affects microglial immunometabolism in obese rats, finding that TRF during the active phase reduces fat mass and alters microglial transcriptome rhythmicity, but does not reverse HFD-induced metabolic inflexibility.

The paper examines neuropathological changes in the nucleus basalis of Meynert in diabetes patients, finding reduced ChAT expression in T1DM and increased hyperphosphorylated-Tau in T2DM.

This study shows that activating microglial PPARdelta with GW0742 improves insulin sensitivity in obese rats without changing body weight or food intake.

This study creates a detailed single-cell RNA-seq atlas of the mouse PVN, identifying transcriptional subtypes and linking them to functional roles.