Author

Laura L. Bahr

University of PittsburghORCID 0000-0002-1200-9307Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:C. elegans· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Arjumand GhaziiD· 3 shared Francis R. G. AmritiD· 2 shared Guled A. Osman· 2 shared Hannah Henry· 2 shared Mayur Nimbadas DevareiD· 2 shared Nikki NaimiD· 2 shared Bella WayhsiD· 1 shared Brooke E Montgomery· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetics

Arjumand GhaziORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A TCER-1-siRNA Regulatory Axis Suppresses Antibacterial Innate Immunity in C. elegans

Nikki Naim, Francis R. G. Amrit, Mayur Nimbadas Devare, Guled A. Osman, Laura L. Bahr, Hannah Henry, Brooke E Montgomery, Spencer Kuhn, Taiowa A. Montgomery, Arjumand Ghazi

The paper identifies a TCER-1-siRNA regulatory axis that suppresses antibacterial innate immunity in C. elegans by targeting immune effectors like scrm-4.

PLoS Pathogens · Jul 28, 2026Peer-reviewedImmunology

Caffeine extends lifespan by enhancing lysosomal lipolysis in Caenorhabditis elegans

Hyemin Min, Eunseok Kang, Gee‐Yoon Lee, Laura L. Bahr, Arjumand Ghazi, Seung‐Jae Lee

This study shows caffeine extends lifespan in C. elegans by enhancing lysosomal lipolysis through a dietary restriction-like transcriptional program.

Molecules and Cells · Apr 16, 2026Peer-reviewedGenetics

LIPL-1 and LIPL-2 are TCER-1-regulated Lysosomal Lipases with Distinct Roles in Immunity and Fertility

Laura L. Bahr, Francis R. G. Amrit, Paige Emily Silvia, Bella Wayhs, Guled A. Osman, Mayur Nimbadas Devare, Hannah Henry, Duc Thien Bui, Mirae Choe, Nikki Naim, Margaret Champion, Yuxuan Man, Carissa Perez Olsen, Arjumand Ghazi

This study identifies LIPL-1 and LIPL-2 as TCER-1-regulated lysosomal lipases with distinct roles in balancing immunity and fertility in C. elegans.

PLoS Genetics · Dec 12, 2025Peer-reviewedGenetics