Author

Guled A. Osman

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Arjumand GhaziiD· 2 shared Francis R. G. AmritiD· 2 shared Hannah Henry· 2 shared Laura L. BahriD· 2 shared Mayur Nimbadas DevareiD· 2 shared Nikki NaimiD· 2 shared Bella WayhsiD· 1 shared Brooke E Montgomery· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersImmunology

Arjumand GhaziORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A TCER-1-siRNA Regulatory Axis Suppresses Antibacterial Innate Immunity in C. elegans

Nikki Naim, Francis R. G. Amrit, Mayur Nimbadas Devare, Guled A. Osman, Laura L. Bahr, Hannah Henry, Brooke E Montgomery, Spencer Kuhn, Taiowa A. Montgomery, Arjumand Ghazi

The paper identifies a TCER-1-siRNA regulatory axis that suppresses antibacterial innate immunity in C. elegans by targeting immune effectors like scrm-4.

PLoS Pathogens · Jul 28, 2026Peer-reviewedImmunology

LIPL-1 and LIPL-2 are TCER-1-regulated Lysosomal Lipases with Distinct Roles in Immunity and Fertility

Laura L. Bahr, Francis R. G. Amrit, Paige Emily Silvia, Bella Wayhs, Guled A. Osman, Mayur Nimbadas Devare, Hannah Henry, Duc Thien Bui, Mirae Choe, Nikki Naim, Margaret Champion, Yuxuan Man, Carissa Perez Olsen, Arjumand Ghazi

This study identifies LIPL-1 and LIPL-2 as TCER-1-regulated lysosomal lipases with distinct roles in balancing immunity and fertility in C. elegans.

PLoS Genetics · Dec 12, 2025Peer-reviewedGenetics

Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans

Kirthi C. Reddy, Tal Dror, Ryan S. Underwood, Guled A. Osman, Corrina R. Elder, Christopher A. Desjardins, Christina A. Cuomo, Michalis Barkoulas, Emily R. Troemel

This study identifies two C. elegans-specific genes, pals-22 and pals-25, which function as antagonistic regulators controlling the switch between growth and pathogen resistance.

PLoS Pathogens · Jan 14, 2019Peer-reviewedGenetics