Renaud Du Pasquier

The paper identifies high neuron-microglia interaction at the node of Ranvier as a predictor of recovery in an inflammatory MS model, showing its association with pro-regenerative microglia and improved tissue repair.

The paper identifies clonally expanded neuron-specific CD8+ T cells in anti-Ri AIE patients using an unbiased approach and shows they express KIR3DL1 and TOX.

This study develops a cell-based assay using human iPSC-derived neurons and astrocytes to detect novel neural-reactive antibodies in patients with immune-mediated neurological diseases, finding higher reactivity in inflammatory disease groups.

This study shows JCPyV infects astrocytes, dysregulates cell biology, and affects excreted vesicles, providing insights into PML pathogenesis.

This study shows that tau-containing extracellular vesicles from neurons transfer tau to astrocytes, disrupting their mitochondrial function, with 3R tau being more damaging than 4R tau.