Author

Shannon T. Smith

Vanderbilt UniversityORCID 0000-0002-1225-8928Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Hope WoodsiD· 2 shared Jens MeileriD· 2 shared Ajasja LjubetičiD· 1 shared Amanda L. LoshbaughiD· 1 shared Amelie SteiniD· 1 shared Ameya HarmalkariD· 1 shared Andrew Leaver‐FayiD· 1 shared Andrew M. WatkinsiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Hope WoodsORCID

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2 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedNov 29, 2021

Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

Julia Koehler Leman, Sergey Lyskov, Steven Macauley Lewis…·Richard Bonneau

The paper presents a framework for ensuring reproducibility in bio-macromolecular modeling through automated benchmarks and a test server, demonstrating its utility for Rosetta and other tools.

26 citations

experimental assaybenchmarking

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 17, 2021

Structural comparative modeling of multi-domain ΔF508 CFTR

Eli Fritz McDonald, Hope Woods, Shannon T. Smith…·Jens Meiler

The paper uses Rosetta comparative modeling to generate structural models of ΔF508 CFTR and its variants, revealing how the mutation destabilizes the protein and how drugs like VX-809 stabilize it.

DOI 10.1101/2021.11.17.468921

humanprotein structure

𝕏 PostBluesky