Author
University of Arkansas at FayettevilleORCID 0000-0001-6615-545XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Matthew Brownd, Stephanie M. Sauve, Hope Woods, Mahmoud Moradi
The paper uses free-energy perturbation to calculate binding affinities of cAMP to HCN isoforms 1-4 CNBDs, revealing differences in channel activation sensitivity.
Baharak Abd Emami, Ahmed Shubbar, Hope Woods…·Reza Dastvan
This study identifies structural dynamics and regulatory mechanisms of SK1, revealing a novel inhibitory paradigm and insights for therapeutic development.
Julia Koehler Leman, Sergey Lyskov, Steven Macauley Lewis…·Richard Bonneau
The paper presents a framework for ensuring reproducibility in bio-macromolecular modeling through automated benchmarks and a test server, demonstrating its utility for Rosetta and other tools.
Eli Fritz McDonald, Hope Woods, Shannon T. Smith…·Jens Meiler
The paper uses Rosetta comparative modeling to generate structural models of ΔF508 CFTR and its variants, revealing how the mutation destabilizes the protein and how drugs like VX-809 stabilize it.