Author

Menuka Karki

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-1234-0024Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

João A. PauloiD· 1 shared Laura FrizziiD· 1 shared Noelle OzimekiD· 1 shared Randall W. KingiD· 1 shared Sandhya ManohariD· 1 shared Steven P. GygiiD· 1 shared Valentina RossioiD· 1 shared Yingqian CheniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperCell Biology

João A. PauloORCID

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintMar 9, 2026

CDK/mTOR-dependent phosphorylation of UBE2H restrains its charging with ubiquitin and regulates CTLH-dependent degradation

Yingqian Chen, Valentina Rossio, João A. Paulo…·Randall W. King

The paper identifies CDK/mTOR-dependent phosphorylation of UBE2H as a regulator of CTLH E3 ligase activity, showing how it controls ubiquitylation and substrate degradation.

2 citations

proteomicsexperimental assay

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