Steven Paraskevas

This study shows that inhibiting RORgamma enhances PD-L1 blockade efficacy in HCC by reducing neutrophil recruitment and increasing PD-L1 expression.

This study shows that reduced NCK1 in beta cells of type 2 diabetes patients impairs the unfolded protein response and insulin secretion, with sex-specific adaptive responses observed in mice.

This paper develops a method to create vascularized bioartificial organs using 3D printing and polymer casting, demonstrating its application in creating a functional pancreas for diabetes treatment.

This study develops a scalable encapsulation method for pluripotent stem cell-derived pancreatic islets, showing improved cell recovery and in vivo functionality during transplantation.

The paper describes a method to create cm-scale perfusable endocrine pancreatic tissues using sacrificial embedded 3D printing in alginate, showing viability and insulin secretion in cultured beta cells.