Author

Christopher L. Pin

Western UniversityORCID 0000-0002-1245-1058Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Fatemeh MousaviiD· 2 shared Mickenzie B. MartiniD· 2 shared Parisa ShooshtariiD· 2 shared Abdessamad El KaoutariiD· 1 shared Angela MathisoniD· 1 shared Charis Johnson· 1 shared Emilie JauneiD· 1 shared Filip BednariD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Fatemeh MousaviORCID

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3 papers

Recent·Most cited

Cell BiologyFEBS JournalPeer-reviewedAug 10, 2025

Defining the SPCA2C interactome identifies unique links to store-operated calcium entry

Petra Samardzija, Melissa A. Fenech, Oneeb Hassan…·Christopher L. Pin

This study identifies novel SPCA2C interactors involved in calcium signaling and vesicular transport using BioID and validates key interactions with STIM1, ESYT1, and CCDC47.

1 citation

humanproteomics

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Cancer BiologyJCI InsightPeer-reviewedDec 31, 2024

EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice

Emilie Jaune, Xiaoyi Wang, Fatemeh Mousavi…·Christopher L. Pin

This study shows EZH2 deletion in adult acinar cells does not block regeneration but limits PDAC progression by altering the tumor microenvironment and differentiation.

3 citations

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintSep 12, 2023

Mouse models for pancreatic ductal adenocarcinoma are affected by the cre-driver used to promote KRASG12D activation.

Fatemeh Mousavi, Joyce Thompson, Justine Lau…·Filip Bednar

This study compares mouse models of pancreatic ductal adenocarcinoma driven by different cre-recombinase systems, finding differences in tumor development and inflammation.

DOI 10.1101/2023.09.12.557383

mousebulk RNA-seq

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