Author

Hannah Elcocks

University of LiverpoolORCID 0000-0002-1248-0684Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Heather MortiboysiD· 1 shared Katy R. McCarroniD· 1 shared Michael J. ClagueiD· 1 shared Sylvie UrbéiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCell Biology

Heather MortiboysORCID

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1 paper

Recent·Most cited

Cell BiologyBiochemical JournalPeer-reviewedFeb 1, 2024

The Parkinson's Disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress

Katy R. McCarron, Hannah Elcocks, Heather Mortiboys…·Michael J. Clague

This study shows that the VPS35 D620N mutation enhances LRRK2 activity and amplifies its response to endolysosomal stress, leading to increased phosphorylation of RAB10 and RAB12.

10 citations

humanproteomics

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