Author

Khaled Sayed

University of PittsburghORCID 0000-0002-1252-3170Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Adam ButchyiD· 1 shared Ana Lucia MoraiD· 1 shared Bokai ZhuiD· 1 shared Cheryl A. TelmeriD· 1 shared Christof KaltenmeieriD· 1 shared Eleanor ValenziiD· 1 shared Kara N. BocaniD· 1 shared Lorena RosasiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Adam ButchyORCID

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2 papers

Recent·Most cited

LEF1 isoforms regulate cellular senescence and aging

Minxue Jia, Khaled Sayed, Maria G. Kapetanaki, William A. Dion, Lorena Rosas, Saad Irfan, Eleanor Valenzi, Ana Lucia Mora, Robert Lafyatis, Mauricio M. Rojas, Bokai Zhu, Panayiotis V. Benos

The paper identifies LEF1 isoforms as key regulators of cellular senescence and aging through transcriptomic analysis and validation in human and mouse models.

Aging Cell · Nov 13, 2023Peer-reviewedGenomics

Computational modeling of cell signaling and mutations in pancreatic cancer

Cheryl A. Telmer, Khaled Sayed, Adam Butchy, Kara N. Bocan, Christof Kaltenmeier, Michael T. Lotze, Nataša Miškov-Živanov

The paper develops a computational model of pancreatic cancer signaling and mutations to identify potential inhibitor combinations for therapy.

bioRxiv · Jun 8, 2021 · PreprintSystems Biology