Synthetic BiologyNature CommunicationsPeer-reviewed
Post-translational covalent assembly of CAR and synNotch receptors for programmable antigen targeting
Elisa Ruffo, Adam Butchy, Yaniv Tivon…·Jason J. Lohmueller
This paper introduces SNAP-CAR and SNAP-synNotch receptors that can be post-translationally targeted by BG-conjugated antibodies to activate T cell signaling or gene programs in an antigen-specific manner.
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