Enforced MYC expression selectively redirects transcriptional programs during human plasma cell differentiation
Panagiota Vardaka, Ben Kemp, Sophie Stephenson, Sophie Stephenson, Matthew A. Care, Michelle Umpierrez, Eleanor O'Callaghan, Eleanor O’Callaghan, Roger G. Owen, Daniel James Hodson, Gina M. Doody, Reuben M. Tooze
This study shows that enforced MYC expression alters transcriptional programs and metabolic shifts during human plasma cell differentiation without causing transformation.
Life Science Alliance · Jul 28, 2025Peer-reviewedCell Biology