MicrobiologybioRxivPreprint
Synergistic latency reversal by the IAP antagonist AZD5582 and BET inhibitor JQ1, combined with Nef ablation, facilitates immune-mediated elimination of latently HIV-1-infected T-cells
Dylan Postmus, Sui Ting Hui, Bengisu Akbil…·Christine Goffinet
This study shows that combining IAP antagonist AZD5582, BET inhibitor JQ1, and Nef ablation enhances immune-mediated elimination of HIV-1 latently infected T-cells.
DOI 10.1101/2025.08.06.668975