Author

Dominic Wooding

Liverpool School of Tropical MedicineORCID 0000-0002-9985-0413Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:virus· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Thomas EdwardsiD· 3 shared Christine GoffinetiD· 2 shared Giancarlo A. BiaginiiD· 2 shared Shaun H. PenningtoniD· 2 shared Susan GouldiD· 2 shared Tom E. FletcheriD· 2 shared Abdulakeem Eniola Amoo· 1 shared Abisola Ajoke Adeyemi· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

Thomas EdwardsORCID

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Author profile →

4 papers

Recent·Most cited

A Multiplex qPCR to Differentiate Monkeypox Virus Clades

Christopher T. Williams, Alessandra Romero-Ramirez, Adesola Semiu Adeleye, Samuel Oluwafunmbi Ifabumuyi, Caitlin Greenland-Bews, Susan Gould, Dominic Wooding, Collette E. Allen, Anushri Somasundaran, Nicodemus Nnabuike Mkpuma, Dorcas A. Gado, Jolly Amoche Adole, Abdulakeem Eniola Amoo, Abisola Ajoke Adeyemi, Laure Bosquillon de Jarcy, , Thomas Edwards

The paper develops a multiplex qPCR assay to differentiate monkeypox virus clades, showing high sensitivity and specificity in clinical samples.

Emerging infectious diseases · Feb 1, 2026Peer-reviewedGenetic & Genomic Medicine

Synergistic latency reversal by the IAP antagonist AZD5582 and BET inhibitor JQ1, combined with Nef ablation, facilitates immune-mediated elimination of latently HIV-1-infected T-cells

Dylan Postmus, Sui Ting Hui, Bengisu Akbil, Jenny Jansen, Dominic Wooding, Oya Cingöz, Christine Goffinet

This study shows that combining IAP antagonist AZD5582, BET inhibitor JQ1, and Nef ablation enhances immune-mediated elimination of HIV-1 latently infected T-cells.

bioRxiv · Aug 6, 2025 · PreprintMicrobiology

Dynamic Culture Improves the Predictive Power of Bronchial and Alveolar Airway Models of SARS-CoV-2 Infection

Claire H Caygill, Rose C. Lopeman, Kirstie A Lewis, Emily Richardson, Aitor Casas-Sánchez, Nick Heavey, Adam Winrow, Louise Howard, Chris Williams, Dominic Wooding, Thomas Edwards, Eric R. Lucas, Tomasz M. Kostrzewski, Andrew Owen, Shaun H. Pennington, Giancarlo A. Biagini

This study compares static and dynamic flow culture conditions in human airway models to show that dynamic flow improves tissue architecture, infection dynamics, and predictive power for SARS-CoV-2 infection.

bioRxiv · Jul 21, 2025 · PreprintMicrobiology

An optimised method for recovery and quantification of laboratory generated SARS-CoV-2 aerosols by plaque assay.

Rachel Louise Byrne, Susan Gould, Thomas Edwards, Dominic Wooding, Barry Atkinson, Ginny Moore, Kieran Collings, Cedric Boisdon, Simon Maher, Giancarlo A. Biagini, Emily Rebecca Adams, Tom E. Fletcher, Shaun H. Pennington

The paper describes an optimized method for recovering and quantifying SARS-CoV-2 aerosols using plaque assay, suitable for integration into BSL3 laboratory protocols.

bioRxiv · Oct 31, 2022 · PreprintMolecular Biology