Author

Antonio Astorga-Gamaza

Universidad Pablo de OlavideORCID 0000-0002-1276-5276Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Inés Muela‐ZarzuelaiD· 2 shared Juan Miguel Suarez-RiveroiD· 2 shared Mario David CorderoiD· 2 shared Alberto SanziD· 1 shared Alejandra Guerra‐CastellanoiD· 1 shared Alessandra TammaroiD· 1 shared Alexis VariniD· 1 shared Auxiliadora MazuecosiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Inés Muela‐ZarzuelaORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 29, 2026

Human NLRP1 and NLRP3 interact driving inflammation in inflammosomopathies and inflammatory diseases

Juan Miguel Suarez-Rivero, Inés Muela‐Zarzuela, Antonio Astorga-Gamaza…·Mario David Cordero

This study identifies a hybrid inflammasome formed by NLRP1 and NLRP3 in human cells, associated with inflammation in inflammasomopathies and transplant patients.

DOI 10.64898/2026.01.26.701718

humanexperimental assay

ImmunologybioRxivPreprintApr 17, 2024

Inflammasome Profiling in Human Natural Killer Cells under Pro-inflammatory Stimuli and Solid Organ Transplantation

Antonio Astorga-Gamaza, Inés Muela‐Zarzuela, Juan Miguel Suarez-Rivero…·Mario D. Cordero

This study shows human NK cells can activate inflammasomes in vitro and in transplant patients, with distinct responses in CD56 subsets and sustained activation in renal dysfunction and transplant rejection.

DOI 10.1101/2024.04.17.589865

humanbulk RNA-seq